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Conundrum of PST: current evidence
Mamounas E, et al. JCO 2012;30:3960-6.
Combined analysis of NSABP B18 and B27
Summary:
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Predictive factors for LRR:
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age
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initial clinical stage prior
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pathological response in breast and axilla
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Impact of age and clinical stage on absolute LRR
rate is low if pCR in breast/axilla
Predictors of LRR after primary chemotherapy