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Several RCTs performed to investigate impact on cosmesis of:

Hypofractionation (40-42 Gy in 15-16 fx) compared to 25 x 2 Gy

Boost vs no boost

Low boost vs high boost

Prone vs supine

IMRT vs 2D-CRT

Partial breast RT vs Whole breast RT

Which

radiotherapy

related factors play a role ?