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Cosmetic results after breast conserving therapy
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Which factors play a role ? Several RCTs to investigate impact of:
Factor studied
Impact on cosmesis
Conclusion
Hypofx
No change in breast
appearance
No boost vs low boost
No boost better than boost
Hypofx:
Whelan 2008; Haviland 2013;
Prone vs supine:
Veldeman 2016;
2D CRT vs IMRT:
Pignol 2016; Mukesh 2014;
No vs low boost:
Vrieling 1999 & 2000, Hau 2013;
Low vs high
boost
: Brouwers 2016;
PBI vs WBRT:
Polgar 2017, Coles 2017, Peterson 2015