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Which factors have all been mentioned to influence cosmetic
outcome and/or fibrosis ?
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Treatment related factors:
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Radiotherapy:
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Boost volume, dose inhomogeneity, V55Gy, Dmax, V107, V110,
IMRT, Prone vs supine, boost dose
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Surgery
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Post-operative complications like infection, hematoma, seroma
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Baseline cosmesis after surgery – prior to RT, location of the
tumor, time between surgery and radiotherapy
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Oncoplastic surgery
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Chemotherapy/ hormonal therapy
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Yes/no
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Concurrent/ sequential
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Patient related factors:
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Age, BMI, smoking, diabetes, breast size, Bra size, pain..