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How to reduce the boost volume ?

Pathology; discuss with your pathologist:

Free margins in 6 directions

smaller delineated CTV

Surgery; discuss with your surgeon:

Limit excision volumes; no tumor on ink is sufficient !

Limit size of seroma cavity

Place clips to reduce uncertainty

to reduce volume

Avoid oncoplastic surgery in case of indication for boost ?

Chemotherapy:

If required anyway: consider to give it upfront

Smaller tumor, smaller

excision volumes.

Consider to give it prior to RT to increase time between OK and RT ?