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Take Home Messages (1)

Cosmetic outcome after BCT varies from 56 - 92%

Interpretation of literature difficult due to differences in endpoints

and duration of follow-up

Most important factor seems to be:

cosmesis prior to RT

Other factors that worsen cosmetic outcome:

Inhomogeneous dose distribution, high EQD2, large boost

volumes, young age, large breast size, smoking,

chemotherapy

Questionable influence:

Endocrine therapy, oncoplastic surgery