Results of the EBCTCG meta-analysis: lumpectomy +/- RT:
Ipsilateral breast events*
EBCTCG JNCI 2010
Incl. Tamoxifen
Conclusion of all analyses:
•
RT reduces LR with factor 2;
•
about 50% of recurrences concerns an invasive recurrence
(~ 40% probability to become invasive if untreated at all)