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Results of the EBCTCG meta-analysis: lumpectomy +/- RT:

Ipsilateral breast events*

EBCTCG JNCI 2010

Incl. Tamoxifen

Conclusion of all analyses:

RT reduces LR with factor 2;

about 50% of recurrences concerns an invasive recurrence

(~ 40% probability to become invasive if untreated at all)