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Positive versus negative margins:

Housami et al. Ann Surg Onc, 2014

Large Meta-analysis of 28000 women undergoing BCS for invasive

cancer, 1506 local recurrences across 33 studies

Overall mean LR rate was 5.3% at 79 months

Relative risk of recurrence 2.44 for positive versus negative margin.

Margin width made no difference