Positive versus negative margins:
•
Housami et al. Ann Surg Onc, 2014
•
Large Meta-analysis of 28000 women undergoing BCS for invasive
cancer, 1506 local recurrences across 33 studies
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Overall mean LR rate was 5.3% at 79 months
•
Relative risk of recurrence 2.44 for positive versus negative margin.
Margin width made no difference