Large Danish Cohort (Bodilsen et al, 2016)
•
11 900 women treated with BCS
•
Median FU 4.9 years
•
Hazard ratio for a positive margin
2.51 but final positive margins very
rare (<1% of population.
•
Chemotherapy reduced risk by about
half but small numbers preclude
assessment according to margin
status
0
1
2
3
4
5
6
7
8
9
10
IBTR
Margin status and IBTR
positive close negative