Summary 1
•
Consistent evidence that
positive margins result in higher
LRR, regardless of
•
Tumour biotype
•
Age
•
Systemic Treatment
•
Boost
•
Uncertainty regarding whether
residual disease is present or not
or whether it is small volume
(and likely to respond to RT/CT)
or large volume.
•
Data shows that local recurrence
at 5 years translates into
increased mortality rates at 15
years (EBCTCG)