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Low Grade
An Evidence Based Approach
Jakola et al. JAMA, 2012
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Population-based natural history study
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153 pt, 2 hospitals serving two different regions
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Treatment dependent on residential address
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A) Biopsy + Watchful waiting
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MS 5,9 yy
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5 year survival: 60%
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B) Maximal safe resection
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No reach of MS by the end of
the study
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5 year survival: 74%