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High Grade gliomas
An Evidence Based Approach
• 33 publications
• Extent of resection
improves TTP and OS
After gross total resection
WHO grade III OS 64.9-75.2 m
WHO grade IV OS 11.3-18.5 m
Recurrent GBM benefits from
gross total resection
(selection bias)
19m total vs 15. for subtotal
Bloch O, Han SJ, Cha S, Sun MZ, Aghi MK, McDermott MW, Berger MS,
Parsa AT (2012) Impact of extent of resection for recurrent glioblastoma on
overall survival: clinical article. J Neurosurg 117:1032–1038