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PHYSIOLOGICAL IMAGING

FUNCTIONAL IMAGING - fMRI

Pitfalls:

• Does not monitor the neural response but a “surrogate” hemodynamic response

• Cannot distinguish essential hubs -> need for intraoperative monitoring

• Low localisation accuracy

Neurovascular uncoupling

(tumor infiltration zone, neovascularity) with reduced

fMRI signal in perilesional cortex

• More accurate for motor mapping than for speech

• Not giving any functional information about subcortical white matter pathways

Finger Tapping

Semantic speech