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PHYSIOLOGICAL IMAGING
FUNCTIONAL IMAGING - fMRI
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Pitfalls:
• Does not monitor the neural response but a “surrogate” hemodynamic response
• Cannot distinguish essential hubs -> need for intraoperative monitoring
• Low localisation accuracy
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Neurovascular uncoupling
(tumor infiltration zone, neovascularity) with reduced
fMRI signal in perilesional cortex
• More accurate for motor mapping than for speech
• Not giving any functional information about subcortical white matter pathways
Finger Tapping
Semantic speech