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DESCRIPTION OF AOAC STATISTICS COMMITTEE GENERATED DOCUMENTS

ALTERNATIVE APROACHES FOR MULTI‐LAB STUDY DOCUMNTS.   

Alternative approaches approved by Committee on Statistics and by OMB. 

1.

*tr322‐SAIS‐XXXV‐Reproducibility‐from‐PT‐data.pdf: Discussion on how 

to obtain reproducibility from proficiency test data, and the issues 

involved. 

……………………………… 

2

2.

tr333‐SAIS‐XLII‐guidelines‐for‐use‐of‐PT‐data.pdf: Recommended use 

of proficiency test data for estimating repeatability and reproducibility. ……………………………… 

8

3.

*tr324‐SAIS‐XXXVII‐Incremental‐collaborative‐studies.pdf: Proposed 

incremental collaborative studies to find repeatability and 

reproducibility via a sequential series of experiments. 

……………………………...

11

4.

tr326‐SAIS‐XXXIX‐Min‐degr‐freed‐for‐random‐factor‐estimation.pdf: 

The relationship of number of replicates or number of collaborators to 

precision of standard deviation for repeatability or reproducibility. 

……………………………… 

19

5.

tr323‐SAIS‐XXXVI‐When‐robust‐statistics‐make‐sense.pdf: Caveats and 

recommendations on the use of so‐called ‘robust’ statistics in 

accreditation studies. 

……………………………… 

21

TRADITIONAL PATHWAY MULTI‐LAB STUDY DOCUMENTS AND INSTRUMENTS.     

Traditional study approach spreadsheet remaining as part of acceptable approaches. 

6.

JAOAC 2006 89.3.797_Foster_Lee1.pdf: Journal article by Foster and 

Lee on the number of collaborators needed to estimate accurately a 

relative standard deviation for reproducibility. 

……………………………… 

29

7.

LCFMPNCalculator.exe: This program analyzes serial dilution assay data 

to obtain a most probable number estimate of concentration with 

confidence interval. 

Separate Program

8.

AOAC_BlindDup_v2‐1.xls: This workbook analyzes multi‐collaborative 

study data with up to 4 replicates and reports all necessary statistics 

concerning repeatability and reproducibility for quantitative studies. 

Separate Program

9.

AOAC‐binary‐v2‐3.xls: This workbook analyzes multi‐collaborative 

study data with arbitrary number of replicates and reports all 

necessary statistics, including POD, repeatability and reproducibility 

with confidence intervals, for binary (presence/absence) qualitative 

studies. 

Separate Program

102