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8

RECOMMENDATIONS

1. Use of ‘robust’ estimators for measures of center location is non-controversial, as the measure

of centrality is based on central data.

2. Use of ‘robust’ estimators for measures of variation or spread is deprecated, as they will be

substantially biased low.

3. A circumstance in which ‘robust’ estimators of variation might be recommended is when:

a. The underlying distribution is

known a priori

to be normally distributed or substantial

additional evidence (other than the actual data in question) supports this assertion.

b. The observed data are

known a priori

to be contaminated with data a foreign distribution, and

this contamination is exclusively found in the tails of the empirical distribution.

c. The outliers present are

known a priori

to not be identifiable for assigned cause.

This circumstance might arise, for example, in PT data where it can be supposed that

substantially different variants of the method in question may be in use, and these variants cannot

be identified from the information collected in the study. Inclusion of all data in such a study may

result in an estimate of reproducibility standard deviation that is

known a priori

to be much too

large.

4. In all other circumstance, reproducibility standard deviation should be estimated in the usual

way after removal of outliers for assignable cause.

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