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EMR
EMT
AEMT
Paramedic
Extended
Hydroxocobalamin (Cyanokit)
Action
Onset
Binds with cyanide ions
Immediate
Indications
Smoke inhalation / Cyanide
Adult Dose
5 grams IVP/IO over 15 minutes
Pediatric Dose
Consult medical control
70 mg/kg IVP/IO over 15 minutes, Maximum 5 grams (5,000mg)
Contraindications
Hypersensitivity to hydroxocobalamin or cyanocobalamin
Adverse Reactions
Abnormal color of urine, erythema (red skin), rash, increased blood pressure, nausea, headache, an injection site
reactions.
Precautions
Do not administer diazepam, dopamine, or sodium thiosulfate through the same line.
If administering other medications, do so through a separate IV line.
Considerations
Hydroxocobalamin interferes with some clinical laboratory blood tests performed at hospitals.
Use on any firefighter removed from a structure via RIT who had their mask off at any point.
Mothers breastfeeding should discontinue until out of their system (approx. 24 hours)
Hydroxocobalamin (Cyanokit
®
)