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EMR
EMT
AEMT
Paramedic
Extended
Tranexamic Acid (TXA)
Action
Onset
Antifibrinolytic
Immediate
3 hour half-life
Indications
Multisystem trauma with internal hemorrhage
Adult Dose
1 g mixed in 50 mL IV bag connected to 10 gtts/mL administration set, and administer over 10 minutes (1 drop
per second)
Pediatric Dose
Not indicated.
Contraindications
Isolated traumatic brain injury, more than 3 hours since injury, patients < 15 years of age, nontraumatic shock
Adverse Reactions
Hypersensitivity
Precautions
Monitor for symptoms of severe allergic reaction and changes in vision
Tranexamic Acid (TXA)