•
RCT (
R
andomised
C
ontrolled
T
rial)
•
True if main purpose is to improve efficacy
(local control and survival)
•
Reduction of avoidable hazards?
Randomisation
Standard treatment
e.g. IMRT (photons)
Experimental treatment
e.g. IMPT (protons)
Evidence-based medicine
Gold standard




