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0%

10%

20%

30%

40%

50%

60%

70%

0 10 20 30 40 50 60 70

Gemiddelde dosis

NTCP (%)

Radiotherapie alleen

Radiotherapie en

chemotherapie

Langendijk

et al

, Radiother Oncol 2013

Photons

Protons

Radiotherapy alone

Chemoradiation

Risk tube feeding dependence (NTCP)

Translation from

Δdose to ΔNTCP

Mean dose superior PCM

Step 3: Clinical benefit

Translate ΔDose into ΔNTCP