846-847 / 1676
•
Burden of assessments:
–
Low burden
•
e.g. blood samples
•
high accrual, high
compliance
–
Intermediate burden
•
e.g. questionnaires
•
high accrual, intermediate
compliance
–
High burden
•
e.g. repeated PET-scans
during treatment
•
low accrual, low compliance
Prospective data registration
Threats for low accrual / low compliance