COMMENT PARAMETERS
USER COMMENTS
AOAC OMA
2011.10
Method Name/Manuscript Title
Vitamin B12 in Infant Formula and Adult Nutritionals
High‐Performance Liquid Chromatography
Manuscript Reference
J. AOAC Int. 95, 313(2012); AOAC SMPR 2011.005
J. AOAC Int. 95, 293(2012)
In your experience using the method, does the
method perform according to the method’s
applicability as written?
Yes
In your experience with the method, is there
any safety concerns identified while using or
regarding use of the method?
Fumes generated during mobile phase preparations (TEA and Formic
Acid) and fumes from oven during heating of samples (cyanide).
Do you have any information that supports
regarding the reproducibility of the method as
written: If so, please specify and submit
information?
None
Please attach any documentation to support
your feedback, if available.
Based on your experience with the method,
are there any recommended changes to the
AOAC First Action Method as written?
Include a note that the method (all preparations) should be carried
out under a fume hood and ensure that oven vent is connected to an
exhaust system.
