97
Antivenoms
black snake antivenom
box jellyfish antivenom
brown snake antivenom
death adder antivenom
funnel-web spider antivenom
redback spider antivenom
sea snake antivenom
stonefish antivenom
taipan antivenom
tiger snake antivenom
Combination products
P
olyvalent
snake
antivenom
concentrate
for
infusion
: brown snake antivenom 1000
U, tiger snake antivenom 3000 U, death
adder antivenom6000 U, taipan antivenom
12,000 U and king brown snake antivenom
18,000 U.
black snake antivenom
Black Snake Antivenom Infusion
Pregnancy risk category NR
Use in sport: Permitted
Available form
Solution for infusion:
18,000 U/vial
Indications & dosages
➤
Treatment of systemic king brown or mulga
snakeenvenoming—
Adults:
18,000 U by slow IV infusion diluted
1 in 10 in Hartmann’s solution, repeated if
necessary.
Children:
18,000 U by slow IV infusion
diluted 1 in 5 in Hartmann’s solution,
repeated if necessary.
Action
Antivenomeffective against venomof black
snake and other members of the
Pseudechis
genus such as red-bellied black snake or
common black snake.
Route Onset
Peak
Duration
IV
Unknown Unknown Unknown
Adverse reactions
CNS:
headache.
GI:
abdominal pain, diarrhoea, nausea,
vomiting.
Skin:
injection site reaction, urticaria, rash.
Other:
allergic reactions,
anaphylaxis
,
delayed serum sickness
, chills, pyrexia.
Interactions
None reported.
Contraindications
Should not be used unless there is evidence
of systemic envenoming with potential for
serious toxic effects.
care considerations
• Black snake venom contains neurotoxins,
myolytic and anticoagulant toxins.
• Monitor FBC, platelets, INR and aPTT on
presentation, immobilisation (if used) and
6 hours thereafter.
• Monitor for signs and symptoms of
bleeding (bruising, bleeding fromgums and
venepuncturesites,epistaxis,gastrointestinal
bleeding, haematuria, altered mental status
suggesting intracranial haemorrhage).
• In individuals with severe consumptive
coagulopathy, fresh frozen plasma and/
or cryoprecipitate should be considered
early.
• As product is sourced from horse plasma,
potential for transmission of infectious
disease cannot be ruled out.
• Not administered by IM injection.
• Venom detection kits should be used to
detect and identify specific venom at the
bite site or in urine where possible.
• Anaphylactic reactions may be more
likely in individuals who are atopic or have
previously received equine serum.
