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Dose and fractionation
•
With HDR BT,
interstitial implants
,
•
twice a day 6 hours apart, 3-5 Gy, to finish the treatment in a
similar time to the LDR techniques, in 4-5 days.
•
Plesiotherapy:
•
In small tumors, 5-10 Gy per fraction 2-3 days per week.
•
In large areas (scalp), 2-3 Gy per day is preferable.
•
intermediate 3-5 Gy per fraction x three days per week
•
Total dose: -- 51-54 Gy (3Gy x 17-18 fractions),
–
44-48 Gy (4 Gy x 11-12 fractions),
–
40-42 Gy (5Gy x 8, 6Gy x 7, 7Gy x 6),
–
35 Gy (7 Gy x 5 fractions).
Montero A, et al. HDR plesiotherapy
with custom-made moulds for the
treatment of non-melanoma skin
cancer. Clin Transl Oncol 2009; 11:760-4
AlamM, et al. The use of brachytherapy
in the treatment of nonmelanoma skin
cancer: a review. J Am Acad Dermatol.
2011; 65(2):377-88.
Maroñas M, Guinot JL, et al. Treatment of
facial cutaneous carcinoma with high-dose
rate contact brachytherapy with customized
molds. Brachytherapy 2011;10(3):221-7.