Systemic radiotherapy in MM:
TBI and HBI
•
Bone marrow ablative (allo and/or auto) preparative
regimens: drugs alone (Melphalan) (more toxicity with TBI)
•
Non myeloablative allogeneic transplantations (mini-allo):
single dose 2 Gy TBI, combined with various chemotherapy
regimens
•
HBI (mainly historical)