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Solitary or localized plasmacytomas are rare diseases that account for less
than 10% of all plasma cell neoplasms
Similar to MM but without infiltration of the bone marrow, these neoplasms
are composed of sheets of plama cells involving bone or soft tissue
When the lesion is isolated in bone, the disorder is called
Solitary
Plasmacytoma of Bone (SPB)
[mostly occurs in the bones of the axial
skeleton]
When in soft tissues, the lesion is called
Extramedullary Plasmacytoma
(EMP)
, and is found in the head and neck 80% of the time
SPBs are found predominantly in men (male-to-female ratio of 2:1) and at a
median age of 55 years (younger age than MM), and are slightly more
common than EMPs