1080 / 1498
What does genetic information add?
•
In the context of appropriate (consistent) histology and
immunophenotype:
•
Confirmation of monoclonal vs polyclonal lymphoid cell
proliferation
•
Demonstration of defining rearrangements e.g.,
IGH-BCL2,
CCND1-IGH, MYC
•
Rearrangements of prognostic value e.g., MYC, IGH-BCL2
and BCL6, API2-MALT1