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What does histology tell us?
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In the context of clinical information about site(s) of
involvement, ‘B’ symptoms etc:
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Small cells (‘-cytes’) vs large cells (-’blasts’) vs mixed
small and large
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Presence and extent of accompanying reactions
(histiocytes, granulomas, eosinophils, fibrosis, necrosis)
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Architectural features: nodular (potentially follicular) vs
diffuse, and mixtures
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Presence of defining cell types; Hodgkin/Reed-Sternberg
cells, popcorn cells, hallmark cells...