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Nivolumab in clinical trials

All B-Cell Lymphoma Patient Responses

Percent Change from Baseline

0

8

16

24

32

40

48

56

64

72

80

88

96

Time since first dose (weeks)

Diffuse Large B-Cell lymphoma

Follicular B-Cell Lymphoma

Other B-Cell Lymphoma

Upper Limit Approximately 540%

Upper Limit Approximately 238%

* **

* **

*

Upper Limit Approximately 615%

Moskowitz C, ASH 2014

-30

-20

-10

0

10

20

30

40

50

60

70

80

90

100

110

120

-40

-50

-60

-70

-80

-90

-100