113 / 1498
R
A
N
D
O
M
I
Z
E
D
CHOP every
21 days
maximum 6 cycles
Rituximab + CHOP
every
21 days
maximum 6 cycles
R
A
N
D
O
M
I
Z
E
D
Observation
Rituximab
maintenance*
*375mg/m
2
every 3 months
for 2 years or until relapse
CR
PR
van Oers MHJ, et al. JCO 2010; 28:2853–2858
EORTC 20981:
Rituximab maintenance vs observation in relapsed FL