1329 / 1498
Zinzani et al. Haematologica 2008;93(9):1364-1371
MALT lymphomas
DLBCL
•
Surgery
is the treatment of choice for localized
presentations
•
Chemotherapy
(anthracycline or fludarabine based
regimens) is the treatment of choice for extensive disease
•
Observation
is a good alternative for asymptomatic
patients with localized disease
•
Radiotherapy
may be an option
(small lesion, histology
available)
•
Recommended first line therapy
includes
anthracycline based CT (CHOP or MACOP-B like
regimens)
•
Surgical resection
requested in some cases
•
Rituximab association with CT needs to be evaluated
within approved clinical trials
•
As for nodal DLBCL, second-line therapy with CT +
ASCT is recommended
RECOMMENDATIONS