The faces of MZL
Extra nodal MZL
Splenic MZL
Nodal MZL
% on MZL
70%
20%
10%
Median age
60
65
50-60
Pathogenesis
Hp, C.jejuni, C.
psittaci, B
burgdoferi
Unknown, HCV
Unknown, HCV
t(11;18)
3q and gain 12q
Nil typical
Typical clinical
presentation
I
E
disease
Abnormal blood
count,
splenomegaly
Adenopathy
Third most common NHL (5-17% of total)