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Other inhibitors of PI3K

Expression

Ubiquitous

Ubiquitous

Leukocytes

Leukocytes

Insulin signaling

Mutated in solid

tumours

Platelet activation

Neutrophil function

Insulin signaling

Mast cell activation

Innate immunity

Immune tracking

B and T cell

activation

Fc receptor

signaling

Idelalisib

IPI-145

Copanlisib

α

β

γ

δ

Class I PI3K

Isoform