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Primary CNS Lymphoma:

A unique lymphoma entity

Increasing incidence

(immunocompetent, older)

PCNSL- Confined to brain (occasionally to eyes and CSF)

Systemic spread is very rare

Multi-centric in the brain in presentation and in relapse

(unlike

gliomas)

Resection is not associated with better outcome

May initially improve and even temporarily disappear with

steroids (may mask a diagnosis)

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