233 / 1498
Risk of breast cancer after RT for HL, by
duration of ovarian function after RT
0
1
2
3
4
5
6
< 10 yrs
10-20 yrs
>=20 yrs
Reference
0.3 [0.2-0.6]
5.3 [2.9-9.9]
years of intact ovarian function after RT
Hazard ratio
Ovarian hormones crucial in radiation-induced breast carcinogenesis
De Bruin et al, JCO 2009