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Literature on CRC risk after HL or childhood cancer
and in A-bomb survivors
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Colorectum: important site of excess cancer in HL survivors
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↑ colon cancer risk after exposure to low RT doses, whereas ↑
rectal cancer risk after higher doses
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Excess CRC risk appears 10 years after exposure
Birdwell et al., 1997; Hodgson et al., 2007; Van den Belt-
Dusebout et al, 2009; Henderson et al 2012 (CCS); Nottage et al
2012 (CCS);Life Span Studies; Eggermond work in progress