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Literature on CRC risk after HL or childhood cancer

and in A-bomb survivors

Colorectum: important site of excess cancer in HL survivors

↑ colon cancer risk after exposure to low RT doses, whereas ↑

rectal cancer risk after higher doses

Excess CRC risk appears 10 years after exposure

Birdwell et al., 1997; Hodgson et al., 2007; Van den Belt-

Dusebout et al, 2009; Henderson et al 2012 (CCS); Nottage et al

2012 (CCS);Life Span Studies; Eggermond work in progress