Integrating Radiotherapy -
Preferred
•
Pre-transplantation RT
as part of the response-inducing regimen
Induce maximal tumor reduction when it is most critical
Differential dose to relapse/bulky site vs. all nodal sites (TLI)
Completed within 10 days (36 Gy b.i.d program)
Safe and rarely toxic
Non-myelosuppressive or leukomogenic