450 / 1498
Phase I/II Trial of TLI vs High-Dose Chemotherapy
Salvage Regimen
Evens et al., Ann Oncol 2007
5-year EFS for TLI/chemo vs chemo alone: 63 vs 6%
(p<0.0001)
5-year OS for TLI/chemo vs chemo alone: 61 vs 27%
(p=0.04)
Predictive factors for EFS: TLI/chemotherapy regimen
Prognostic factors for OS: B-symptoms at relapse