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Rituximab-Chemotherapy in

Untreated Advanced Follicular NHL

Study

Treatment, n

Median

FU,

months

ORR,

%

CR,

%

Median TTP/

TTF/ EFS,

mo

OS,

%

Marcus

et al. 2008

CVP, 159

R-CVP, 162

53

57

81

10

41

15

34

P

<.0001

77

83

P

=.0290

Hiddemann

et al. 2005

CHOP-IFN, 205

R-CHOP-IFN, 223

18

90

96

17

20

29

NR

P

<.001

90

95

P

=.016

Herold

et al. 2007

MCP-IFN, 96

R-MCP-IFN, 105

47

75

92

25

50

26

NR

P

<.0001

74

87

P

=.0096

Salles

et al. 2008

CHVP-IFN, 183

R-CHVP-IFN, 175

42

73

84

63

79

46

67

P

<.0001

84

91

P

=.029