Treatments approaches for those requiring
treatment (high tumour burden)
General approach : rituximab and ……
–
alkylating agents +/- anthracycline
–
Bendamustine / Purine analogues
–
alternative non chemotherapy options
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Radioimmunotherapy
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Lenalidomide and rituximab
–
New generation anti-CD20 antibodies (Ofatumumab, GA101
[Obinutuzumab]).