581 / 1498
Goals of therapy versus toxicity / tolerability in
Follicular Lymphoma
•
FL generally considered incurable - most patients will require additional
therapy in their lifetime.
•
First line treatment options trade off between remission duration versus
toxicity. Eg R-CHOP induces more durable remissions relative to R-CVP
but carries more short-term toxicity and more risk for late cardiotoxicity
•
In absence of proven OS advantage for one choice versus another, no one
‘‘right’’ approach.
•
Treatment decision is patient-specific, incorporating goals of treatment with
the patient’s unique situation
–
Age, comorbidities, tumour burden, patient preferences.