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Background and open questions
R-Chemotherapy plus mediastinal IFRT
is considered the standard treatment for
PMBCL (3-yrs PFS: 80-85%)
Does mediastinal IFRT still improve the outcome in PMBCL patients treated with R-
CHOP/R-CHOP like chemotherapy?
Is a negative PET-CT scan a reliable indicator of cure following chemotherapy
alone, making unnecessary consolidation RT?