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Study aim

To spare the mediastinal radiotherapy (RT) in patients with

“negative PET” after a combined chemo-immunotherapy

Primary endpoint

Progression free survival (PFS) at 2-years from randomization

Secondary endpoints

Overall survival (OS) at 5-years from registration

To define long term toxicities in this patient population

I

NTERNATIONAL

E

XTRANODAL

L

YMPHOMA

S

TUDY

G

ROUP