•
Modelling studies
:
suggest a
significant reduction in the risk of SMN
.
For a
paediatric patient with an
orbital RMS by a factor
of 2
[Miralbell 2002, Paganetti 2012, Taddei 2015]
.
and
for a MB case undergoing
CSI by a factor of 8-15
when
compared with IMRT or XRT
[Miralbell 2001].
Notably, protons provided
more risk reduction for larger
than smaller RT
volumes
.