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Target volume definition

Clinical Target Volume (

CTV

): the

CTV includes the GTV

with

an added margin to treat subclinical microscopic disease

and is

anatomically confined

(i.e. the CTV is limited to the confines of the

bony calvarium, falx and tentorium or extend up to but not beyond

neuroanatomic structures surely not invaded by tumor).

The

CTV margin will be 0.5 cm

for all patients.

Planning Target Volume (

PTV

): the PTV is a geometric expansion

of the CTV to take in to account for uncertainties in immobilisation,

daily patient positioning and image registration.

The

PTV margin will be 0.3 cm - 0.5

cm in all directions.

The size of the required margins will depend on the quality of the

immobilization device chosen and the departmental reproducibility

records for the patient position and chosen device.

SIOP Ependymoma II -

PTV1 target volume

Intracranial ependymoma