260 / 1708
• n = 47 recurrences (1. RT 54-59.4 Gy)
• 29 x OP+CTX vs. 18 x reRT (50.4 – 59.4 Gy +/- CSA) +/-OP
• No higher grade acute toxicity
•
7 vs 81% OS after 3 yrs. - / + reRT
• Late adverse events: endocrine dysfunction, neurocognitive issues