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Target Volumes

Gross Tumour Volume (

GTV

): the GTV includes

all the measurable pathological

tissue with or without

contrast enhancement after surgery/ies

as documented by MRI at the end of

conformal treatment to tumour bed.

Clinical target Volume (

CTV

):

CTV=GTV

i.e. no additional margin to be applied to

GTV for CTV. This is to restrict the boost volume as far as possible, in view of the

likely adjacency of the brainstem for most patients, the hypofractionated schedule

and the resulting cumulative biological effective dose.

Planning Target Volume (

PTV

): the PTV is a geometric expansion of the GTV/CTV

to take in to account for

uncertainty in immobilisation, daily patient positioning and image registration. The

PTV margin is 0.2-0.3 cm

in all directions according to local policies.

SIOP Ependymoma II –

PTV2 boost target

volume

Intracranial ependymoma