276 / 881
Parameters for clinical outcome: Rectum
LQ equivalent dose in 2 Gy fractions (Gy)
Volume [%]
0
20
40
60
80
100
10
20
30
40
50
60
70
80
90
Dose-Volume limits for > G2 rectal toxicity with LQ corrected doses (
α/β
= 3 Gy)
Michalski JM et al. Radiation Dose-Volume effects in radiation-induced rectal injury.
Int. J. Radiation Oncology Biol. Phys., Vol. 76, No. 3, Supplement, pp. S123–S129, 2010.
V50
V60
V65
V70
V75
CTCAE G2
:
Symptoms not
interfering
with ADL; medical
intervention indicated
RTOG G2
: Increase of
4-6 stools/day, or
nocturnal stools, or
moderate cramping