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T Rancati et al. Inclusion of clinical risk factors into NTCP modeling of late rectal toxicity

after high dose radiotherapy for prostate cancer. Radiother Oncol 100 (2011) 124–130.

Parameters for clinical outcome: Rectum

Multivariate modeling for detecting rectal toxicity (G3 late rectal bleeding)

;

1

1

50

k

EUD

TD

NTCP

+

=

Logistic regression:

n

i

n

i

i

Dv

EUD





=

1

n

:

0.046

TD

50

: 93.1

Gy

k

:

10.4

TD

50

: 82.5

Gy

TD

50

: 91.7

Gy