320-321 / 435
SPIFAN Expert Review Panel Report
October 2, 2012
Final
Method
Method Title
Comments
Reviewer(s)
Recommendation
VitA‐01
2011.07 ‐ Vitamins A Infant Formula and
Adult/Pediatric Nutritional Formula by UPLC‐UV or
FLD. Submitted by Nestlé
Don Gilliland
Withdrawn by author
VitA‐09
2011.15 ‐ Determination of Vitamins A (retinol) and E
(alpha‐tocopherol) in Infant Formula and
Adult/Pediatric Nutritional Formula by liquid
chromatography. Submitted by General Mills
No further study will be done
No SPIFAN matrices
Sneh Bhandari
Guifeng Jiang
No action taken by ERP
VitA‐16
Vitamin A & E Single Laboratory Validation 2011.08.
Submitted by Abbott Nutrition
Editorial comments
o
Micrograms not IU
Stability issues with reconstitution
Dry blended
Scott Christiansen
Jinchuan Yang
Recommend for First Action
Official Methods
SM
status
VitA‐17
Simultaneous Determination of Vitamins A, E and
Beta Carotene/Mixed Carotenoids in Infant Formula
by Normal Phase HPLC. Submitted by Pfizer Nutrition
Provide addition on SPIFAN matrices
Explain why the accuracy is at fall out
Analysis of retinol
Erik Konings
Guifeng Jiang
Recommend for First Action
Official Methods
SM
status
Method
Method Title
Comments
Reviewer(s)
Recommendation
VitD‐01
2011.11 ‐ AOAC SPIFAN Single Laboratory Validation
for Vitamin D Analysis in Infant Formula and Adult
Nutritionals and Addendum No. 1a. Submitted by
Covance Laboratories
No data on vitamin D
2
Brendon Gill
Sneh Bhandari
Recommend for Candidate
Dispute Resolution method
VitD‐14
A rapid analytical method for cholecalciferol (vitamin
D3) in fortified infant formula, milk and milk powder
using Diels−Alder derivaƟsaƟon and liquid
chromatography−tandem mass spectrometric
detection. Submitted by Fonterra
Need additional data
o
Require D
2
data
Sneh Bhandari
John Austad
No Decision
VitD‐15
Quantification of vitamin D3 in feed, food, and
pharmaceuticals employing high performance liquid
chromatography‐tandem mass spectrometry.
Submitted by DSM
Only measures D
3
Estela Kneeteman
Brendon Gill
No Decision
VitD‐16
Simultaneous Determination of Vitamin D3 and D2 by
ESI LC‐MS/MS. Submitted by Abbott Nutrition
Clarify precision on adult nutrition
D
3
recovery to be clarified
Present the data
Include blanks as well as SRM
Jeanne Rader
Guenther Raffler
Recommend for First Action
Official Methods
SM
status
AOAC OMB Meeting Book
300