146
Biophysical Society 58
th
Annual Meeting, San Francisco, California
Voltage-gated K Channels II
(Boards #B399–#B428)
2707-P
os
B
oard
#B399
CALCIUM-ACTIVATED K CHANNEL REGULATES CELL
VIABILITY IN HYPERKALEMIC AND HYPOKALEMIC
CONDITIONS: IMPLICATION IN THE NEUROMUSCULAR
DISODERS.
Domenico Tricarico
, Antonietta Mele, Sara Calzolaro,
Giulia Maria Camerino, Diana Conte
2708-P
os
B
oard
#B400
STOCHASTIC MODELING OF CA
2+
-CHANNEL /
BKCA-CHANNEL COMPLEXES.
Daniel H. Cox
2709-P
os
B
oard
#B401
THE CYTOCHROME C-LIKE DOMAIN OF THE HUMAN
BK CHANNEL.
Taleh Yusifov
, Roshni V. Madhvani, Riccardo Olcese
2710-P
os
B
oard
#B402
ENZYMATIC ACTIVITY OF THE HUMAN BK CHANNEL:
A FUNCTION BEYOND ELECTRICAL SIGNALING.
Taleh Yusifov
,
Nicoletta Savalli, Antonios Pantazis, Riccardo Olcese
2711-P
os
B
oard
#B403
BK
β
1 TRANSMEMBRANE REGIONS CRITICALLY CONTROL
THE CHARACTERISTIC PHENOTYPE OF
β
1-CONTAINING
BK CHANNEL CURRENTS.
Guruprasad Kuntamallappanavar
,
Anna N. Bukiya, Alex M. Dopico
2712-P
os
B
oard
#B404
PHOSPHORYLATION OF A CONSTITUTIVE SERINE (S642)
IN BK CHANNEL VARIANTS CONTAINING THE ALTERNATE
EXON ‘SRKR’ ALTERS CURRENT PROPERTIES. Joshua P. Whitt,
Chris Shelley,
Andrea L. Meredith
2713-P
os
B
oard
#B405
UNCOVERING MITOBK
CA
CHANNEL MITOCHONDRIAL
TRANSLOCATION MECHANISMS.
Jin Zhang
, Zhu Zhang,
Enrico Stefani, Ligia Toro
2714-P
os
B
oard
#B406
PROTEOMIC ANALYSIS IDENTIFIES MAXIK CHANNEL
INTRACELLULAR PARTNERS FROM HUMAN CORONARY
ARTERY.
Min Li
, Zhu Zhang, Jure Marijic, Enrico Stefani, Ligia Toro
2715-P
os
B
oard
#B407
ALL-OR-NONE EFFECT OF
γ
1
AUXILIARY SUBUNIT ON BK
CHANNEL GATING.
Vivian Gonzalez-Perez
, Xiao-Ming Xia,
Christopher Lingle
2716-P
os
B
oard
#B408
CYTOSOLIC ACTIVATION DYNAMICS IN THE KV CHANNEL
PROBED BY A FLUORESCENT UNNATURAL AMINO ACID.
Tanja Kalstrup
, Rikard Blunck
2717-P
os
B
oard
#B409
OFFSETTING THE ELECTRIC FIELD SENSED BY K
V
CHANNELS
THROUGH RESIDUE SUBSTITUTIONS ON TOP OF S1.
Evelyn Martinez-Morales,
Alain J. Labro
, Dirk J. Snyders
2718-P
os
B
oard
#B410
ALLOSTERIC COUPLING OF THE INNER ACTIVATION
GATE TO THE OUTER PORE OF A POTASSIUM CHANNEL.
Chris Peters
, David Fedida, Eric Accili
2719-P
os
B
oard
#B411
ENHANCEMENT OF C-TYPE INACTIVATION BY EXTERNAL
CA
2+
AND LA
3+
.
Clay M. Armstrong
2720-P
os
B
oard
#B412
SHAKER KV CHANNEL’S SUGAR REMOTION IN REAL-TIME.
Angelica M. Lopez-Rodriguez
, Gaurav Venkataraman, Miguel Holmgren
2721-P
os
B
oard
#B413
LOCKING THE OPEN STATE OF A VOLTAGE-DEPENDENT
CONCATEMER POTASSIUM CHANNEL WITH METAL
BRIDGES.
Angel A. de la Cruz Landrau
, Miguel Holmgren
2722-P
os
B
oard
#B414
MUTATIONS IN THE CAVITY AFFECT THE RATE OF SLOW
INACTIVATION IN SHAKER K
+
CHANNELS. Tibor G. Szanto,
Orsolya Szilagyi, Florina Zakany,
Gyorgy Panyi
2723-P
os
B
oard
#B415
VOLTAGE SENSOR DOMAIN MUTATIONS INVOLVED IN THE
KV1.2 CHANNEL ACTIVATION VIA MD SIMULATIONS.
Cristiano Amaral
2724-P
os
B
oard
#B416
ATOMISTIC MODELING OF ION CONDUCTION THROUGH
VOLTAGE-SENSING DOMAINS. Mona L. Wood,
J. Alfredo Freites
,
Francesco Tombola, Stephen H. White, Douglas J. Tobias
2725-P
os
B
oard
#B417
CAUTION IS NEEDED IN INTERPRETATION OF ARGàCYS
MUTATION + MTS REACTION IN THE S4 TRANSMEMBRANE
SEGMENT OF A VOLTAGE SENSING DOMAIN (VSD) OF A
VOLTAGE GATED CHANNEL: RESULTS OF QUANTUM
CALCULATIONS. Alisher M. Kariev,
Michael E. Green
2726-P
os
B
oard
#B418
QUANTUM CALCULATIONS SHOW HOW THE WATER AT THE
GATE OF THE VOLTAGE GATED KV1.2 CHANNEL PLAYS A
MAJOR ROLE IN DETERMINING CONDUCTION THROUGH
THE GATE.
Alisher M. Kariev
, Philipa Njau, Michael E. Green
2727-P
os
B
oard
#B419
TURNING A SMALL INTO LARGE CONDUCTANCE K-CHANNEL
- HOW FAR CAN WE GO?
Ignacio Diaz-Franulic
, Nieves Navarro,
Fernando Gonzalez-Nilo, Romina V. Sepulveda, David Naranjo
2728-P
os
B
oard
#B420
AMINO ACID SUBSTITUTIONS FOR T75 IN KCSA ALTER ION
SELECTIVITY. Melia Tabbakhian, Van Ngo, Stephan Haas,
Robert Farley
2729-P
os
B
oard
#B421
ION PERMEATION EFFICIENCY THROUGH POTASSIUM
CHANNELS.
David A. Kopfer
, Chen Song, Ulrich Zachariae,
Bert L. de Groot
2730-P
os
B
oard
#B422
STRATEGIES TO ACHIEVE SELECTIVE CONDUCTANCE IN
K- AND NA- SELECTIVE ION CHANNELS.
Yibo Wang
,
Chunfeng Zhao, Sergei Yu. Noskov
2731-P
os
B
oard
#B423
INSIGHTS INTO THE ION PERMEATION PROCESS OF HIGH
AND LOW CONDUCTANCE K-CHANNELS USING NON-
EQUILIBRIUMMOLECULAR DYNAMICS.
Fernando D. Gonzalez-Nilo
,
Romina Sepulveda, David Naranjo, Daniel Aguayo, Ingrid Araya,
Ignacio Varas, Felipe Bravo, Ignacio Diaz-Franulic, Valeria Marquez-Miranda
2732-P
os
B
oard
#B424
2D IR AS AN EXPERIMENTAL PROBE OF ION-INDUCED
STRUCTURAL CHANGES IN KCSA.
Paul Stevenson
,
Christoph Götz, Carlos R. Baiz, Alipasha Vaziri, Andrei Tokmakoff
